Projects

ON-GOING GOVT. RESEARCH PROJECTS

1.Synthesis, Biological Evaluation & QSAR study of some Piperidine analogs, cyclized bioisosteres of glutamic acid derivatives with an aim of designing pharmacophore of glutamic acid antagonist as an antineoplastic agent.  

PRINCIPAL INVESTIGATOR: – PROF. (DR.) SUBRATA SEN, Principal, C. P. S.

2.Protein-Family-based drug design: Targeting angiogenesis for cancer therapy.

PRINCIPAL INVESTIGATOR:- MR. RAMESH CHANDRA DAS, Asso. Prof., C. P. S.

3.Synthesis, Biological Evaluation & QSAR study of N-2-(Pyridinyl sufonyl) glutamic acid amides, hydrazides and its analogs, and N-(Pyrole-2-yl sulfonyl) glutamic acid amides, hydrazides and its analogs as antineoplastic agents.

PRINCIPAL INVESTIGATOR:- MR. KOUSHIK SARKER, Asso. Prof., C. P. S.

4.Synthesis, Biological Evaluation & QSAR study of N-(8-Quinolinoyl   sulfonyl)   glutamic acid amides & hydrazides.

PRINCIPAL INVESTIGATOR:- MR. AVIJIT GHOSH, Asso. Prof., C. P. S.

5.Stability study of duloxetine on RP-HPLC and characterization of degraded compounds through retro-synthesis.

PRINCIPAL INVESTIGATOR: – MR. TAPAS KUMAR LAHA, Asso. Prof., C. P. S.

6.Synthesis, biological evaluation & QSAR of N-(p-Ethoxy phenyl sulfonyl) glutamic acid analogs and N-(p-Ethoxy phenyl sulfonyl) piperidine 2,4-dicarboxylic acid analogs as possible anticancer agents.

PRINCIPAL INVESTIGATOR:- MR. SUVASISH MISHRA, Asso. Prof., C. P. S.

7.Metabolism and pharmacokinetics study of few Aryl suphonyl -L-glutamic acid and its analogs.

PRINCIPAL INVESTIGATOR:- MRS. MADHULITA PANDA, Asso. Prof., C. P. S.

8.Synthesis, in vitro and in vivo Anti tumor, Antiangiogenic & Apoptosis enhancement study of few N-(2-benzo[b]thiophene sulphonyl) Glutamic acid & it’s analogs.

PRINCIPAL INVESTIGATOR:- MR. ABHIJIT SAHA, Asso. Prof., C. P. S.

9.Fragment based design of focused VEGFR-2 and EGFR protein tyrosine kinase inhibitors: Lead generation, synthesis and their pharmacological evaluation as anticancer and antiangiogenic agents.

PRINCIPAL INVESTIGATOR:- MR. GOURAB SAHA, Asst. Prof., C. P. S.

10.Metabolism and pharmacokinetics study of few 2-(Benzene sulphonamido) pantan-1,5-dioic acid; Probable anticancer agents.

PRINCIPAL INVESTIGATOR:- MISS NILUFA YEASMIN, Asso. Prof., C. P. S.

11.Determination of anti-angiogenic pathway of N-(1,5-Bis(2-(4-nitrophenyl)hydrazinyl)-1, 5-dioxopentan-2-yl)-3, 4-dimethoxy benzene sulphonamide through cell biology study. 

PRINCIPAL INVESTIGATOR:- MRS. PRANGYA PARIMITA PANDA, Asst. Prof., C. P. S.